Green light-mediated dual eosin Y/PdII-catalyzed C(sp2)–H arylation of N–H unprotected 2-arylquinazolinones

Abstract

We report herein an eosin Y/Pd(II) dual catalytic approach for regio- and chemoselective C(sp²)–H monoarylation of N–H unprotected 2-phenyl quinazolinone derivatives under green light irradiation with no necessity for any base/additive/external oxidant. The free N–H moiety was post-modified for quinazolinone scaffold diversification and C–H annulation.