Issue 14, 2024

CinNapht AIE(E)gens for selective imaging of lipid droplets

Abstract

This article describes the synthesis and photophysical properties of Aggregation-Induced Emission (enhancement) luminogens derivated from CinNaphts dyes. These fluorophores can be obtained in good yields in a single SNAr step of a fluorinated CinNapht derivative by incorporating hindered aromatic amines. They exhibit AIE(E) behavior associated with solid-state fluorescence covering an emission range from 563 to 722 nm. One carbazole derivative demonstrates a remarkable efficiency in imaging lipid droplets in living cells through an original photophysical mechanism.

Graphical abstract: CinNapht AIE(E)gens for selective imaging of lipid droplets

Supplementary files

Article information

Article type
Communication
Submitted
16 Feb 2024
Accepted
07 Mar 2024
First published
12 Mar 2024

Org. Biomol. Chem., 2024,22, 2739-2743

CinNapht AIE(E)gens for selective imaging of lipid droplets

E. Tacke, M. Hoang, L. Estaque, P. Durand, G. Pieters and A. Chevalier, Org. Biomol. Chem., 2024, 22, 2739 DOI: 10.1039/D4OB00247D

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