Issue 9, 2024

Terpenoids of plants from Chloranthaceae family: chemistry, bioactivity, and synthesis

Abstract

Covering: 1976 to December 2023

Chloranthaceae is comprised of four extant genera (Chloranthus, Sarcandra, Hedyosmum, and Ascarina), totaling about 80 species, many of which have been widely used as herbal medicines for diverse medical purposes. Chloranthaceae plants represent a rich source of structurally interesting and diverse secondary metabolites, with sesquiterpenoids and diterpenoids being the predominant structural types. Lindenane sesquiterpenoids and their oligomers, chemotaxonomical markers of the family Chloranthaceae, have shown a wide spectrum of bioactivities, attracting significant attention from organic chemists and pharmacologists. Recent achievements also demonstrated the research value of two unique structural types in this plant family, sesquiterpenoid–monoterpenoid heterodimers and meroterpenoids. This review systematically summarizes 682 structurally characterized terpenoids from 22 Chloranthaceae plants and their key biological activities as well as the chemical synthesis of selected terpenoids.

Graphical abstract: Terpenoids of plants from Chloranthaceae family: chemistry, bioactivity, and synthesis

Supplementary files

Article information

Article type
Review Article
Submitted
30 Jan 2024
First published
29 May 2024

Nat. Prod. Rep., 2024,41, 1368-1402

Terpenoids of plants from Chloranthaceae family: chemistry, bioactivity, and synthesis

B. Zhou and J. Yue, Nat. Prod. Rep., 2024, 41, 1368 DOI: 10.1039/D4NP00005F

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