Targeted design of heterotrimetallic 1-D coordination polymers based on functionalized metallocenes featuring antibacterial activity

Abstract

Using (bis)diethoxyphosphoryl ferrocene [Fc(OP(OEt)₂)₂] and transition metal carboxylates – [M₂(μ-OOCR)₄(CH₃CN)₂], M = Cu^II, R = ^tBu, (C₅H₄)Mn(CO)₃ (Cym) or [M₃(μ-OOCR)₆(CH₃CN)₂], M = Ni^II, Co^II, R = Cym, a series of heterometallic polymers with metal cores {Cu₂Fe}_n (1), {Cu₂Mn₄Fe}_n (2) {Ni₂Mn₄Fe}_n (3), and {Co₂Mn₄Fe}_n (4) were obtained under mild conditions. Compounds 1 and 2 showed antibacterial activity against a Mycobacterium smegmatis strain in vitro.