Amphiphilic cyclodextrin derivatives with antibacterial activity: chemical mutation and structure–activity relationship

Hatsuo Yamamura; Ayame Kato; Eri Yamada; Hisato Kato; Takashi Katsu; Kazufumi Masuda; Kayo Osawa; Atsushi Miyagawa

doi:10.1039/D4NJ01874E

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Amphiphilic cyclodextrin derivatives with antibacterial activity: chemical mutation and structure–activity relationship†

Hatsuo Yamamura,

*^a Ayame Kato,^a Eri Yamada,^a Hisato Kato,

^b Takashi Katsu,^b Kazufumi Masuda,^b Kayo Osawa^c and Atsushi Miyagawa^a

Author affiliations

* Corresponding authors

^a Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466-8555, Japan
E-mail: yamamura.hatsuo@nitech.ac.jp

^b Graduate School of Clinical Pharmacy, Shujitsu University, 1-6-1 Nishigawara, Naka-ku, Okayama-shi, Okayama 703-8516, Japan

^c Division of Health Science, Department of Medical Technology, Kobe Tokiwa University, Kobe 653-0838, Japan

Abstract

The relationship between the membrane-disrupting antibacterial activities and the structures of cyclodextrin derivatives containing cationic and hydrophobic moieties was investigated.

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Article information

DOI: https://doi.org/10.1039/D4NJ01874E
Article type: Paper
Submitted: 23 Apr 2024
Accepted: 13 Jun 2024
First published: 26 Jun 2024

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New J. Chem., 2024,48, 12355-12361

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Amphiphilic cyclodextrin derivatives with antibacterial activity: chemical mutation and structure–activity relationship

H. Yamamura, A. Kato, E. Yamada, H. Kato, T. Katsu, K. Masuda, K. Osawa and A. Miyagawa, New J. Chem., 2024, 48, 12355 DOI: 10.1039/D4NJ01874E

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New Journal of Chemistry

Amphiphilic cyclodextrin derivatives with antibacterial activity: chemical mutation and structure–activity relationship†

Abstract

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Amphiphilic cyclodextrin derivatives with antibacterial activity: chemical mutation and structure–activity relationship

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