Issue 22, 2024

Nanoengineered Fe3O4–GO nanoscrolls: exploring the biofunctional applications through magnetic, optical, structural, and morphological analyses

Abstract

Magnetic hybrids with exceptional magnetic and optical properties have emerged as promising materials for diverse applications. In the present work, magnetite (Fe3O4)-functionalized graphene oxide (GO) was synthesized using a facile in situ coprecipitation synthesis method. The in situ formation of Fe3O4 nanoparticles in the presence of GO led to the self-assembly of GO sheets into nanoscrolls. The structural and morphological properties of the nanoscrolls were evaluated. The optical properties were studied using UV-Vis absorbance spectroscopy. Magnetic response assessment by vibrating sample magnetometer confirmed that Fe3O4–GONS had a good superparamagnetic property with maximum saturation magnetization of 54.4 (± 0.5) emu gm−1. The superparamagnetic blocking temperature of the FGO 1 sample was evaluated by temperature-dependent magnetization studies. The in vitro cytotoxicity of the prepared nanocomposites was investigated using an MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay on a fibroblast L929 cell line. The cell viability studies reveal that all the Fe3O4–GO nanohybrids exhibit excellent cell viability (above 80%) compared to that of the control sample. It is worth noting that the magnetic functionalization of GO with Fe3O4 and the scroll structure is a way to enhance the biocompatibility. This work suggests the promise of using multifunctional Fe3O4–GO hybrids in biomedical applications.

Graphical abstract: Nanoengineered Fe3O4–GO nanoscrolls: exploring the biofunctional applications through magnetic, optical, structural, and morphological analyses

Supplementary files

Article information

Article type
Paper
Submitted
07 Feb 2024
Accepted
28 Apr 2024
First published
04 May 2024

New J. Chem., 2024,48, 9931-9944

Nanoengineered Fe3O4–GO nanoscrolls: exploring the biofunctional applications through magnetic, optical, structural, and morphological analyses

M. Rafi, A. Mayeen, H. John and P. Gopinath, New J. Chem., 2024, 48, 9931 DOI: 10.1039/D4NJ00653D

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