Issue 3, 2024

Mechanochemical synthesis of β-cyclodextrin urea derivatives under reactive CO2 atmosphere by Staudinger aza-Wittig reaction

Abstract

Various ureido β-cyclodextrins can be easily synthesised by mechanochemistry from azido-β-cyclodextrins, carbon dioxide and amino derivatives. The reaction was carried out with short reaction times, without solvents and without thermal activation, greatly reducing the environmental impact of the synthesis.

Graphical abstract: Mechanochemical synthesis of β-cyclodextrin urea derivatives under reactive CO2 atmosphere by Staudinger aza-Wittig reaction

Supplementary files

Article information

Article type
Paper
Submitted
13 Mar 2024
Accepted
03 Jun 2024
First published
04 Jun 2024
This article is Open Access
Creative Commons BY-NC license

RSC Mechanochem., 2024,1, 228-234

Mechanochemical synthesis of β-cyclodextrin urea derivatives under reactive CO2 atmosphere by Staudinger aza-Wittig reaction

S. Nasri, M. Lestoquoy, A. Ponchel, E. Monflier and S. Menuel, RSC Mechanochem., 2024, 1, 228 DOI: 10.1039/D4MR00020J

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