Chemoselective Luche-type reduction of α,β-unsaturated ketones by aluminium hydride catalysis

Abstract

A novel, simple, eco-friendly, non-toxic aluminium catalyst was synthesised for the chemoselective reduction of α,β-unsaturated ketones. A wide range of ketones were achieved with excellent yields, mild conditions, and low catalyst loading. Furthermore, this unprecedented method allowed for the stereoselective reduction of natural ketones.