Chemical synthesis of natural and azido-modified UDP-rhamnose and -arabinofuranose for glycan array-based characterization of plant glycosyltransferases

Abstract

Chemical syntheses of UDP-rhamnose and UDP-arabinofuranose and respective azido-modified analogues are reported. The prepared substrates are useful for the glycan array-based analysis of glycosyltransferases, as exemplified with the plant cell wall-biosynthetic enzymes PvXAT3, AtRRT4 and PtRRT5.

Supplementary files

Article information

Article type
Communication
Submitted
30 Apr 2024
Accepted
26 Jul 2024
First published
29 Jul 2024

Chem. Commun., 2024, Accepted Manuscript

Chemical synthesis of natural and azido-modified UDP-rhamnose and -arabinofuranose for glycan array-based characterization of plant glycosyltransferases

I. Pasini, C. Ruprecht, U. Osswald, A. Bittmann, L. Maltrovsky, C. Romanò, M. H. Clausen and F. Pfrengle, Chem. Commun., 2024, Accepted Manuscript , DOI: 10.1039/D4CC02095B

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