Issue 47, 2024

An Au bipyramids@CuZn MOF core–shell nanozyme enables universal SERS and a colorimetric dual-model bioassay

Abstract

In this study, a new type of gold nano-bipyramids@CuZn bimetallic organic framework (AuNBPs@CuZn MOF) nanozyme with high peroxidase (POD)-like activity and surface enhanced Raman scattering (SERS) activity was constructed with a special core–shell structure, which can catalyze the oxidation of TMB (colourless and Raman-inactive) into ox-TMB (blue and Raman-active). An AuNBPs@CuZn MOF-enabling universal SERS and colorimetric dual-model bioassay was thus developed for biomolecules with excellent performance, and has promising application prospects in the biosensing fields.

Graphical abstract: An Au bipyramids@CuZn MOF core–shell nanozyme enables universal SERS and a colorimetric dual-model bioassay

Supplementary files

Article information

Article type
Communication
Submitted
07 Apr 2024
Accepted
08 May 2024
First published
13 May 2024

Chem. Commun., 2024,60, 6019-6022

An Au bipyramids@CuZn MOF core–shell nanozyme enables universal SERS and a colorimetric dual-model bioassay

M. Wang, F. Shi, J. Li, L. Min, Z. Yang and J. Li, Chem. Commun., 2024, 60, 6019 DOI: 10.1039/D4CC01602E

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