Issue 20, 2024

Dual space divergence in small molecule quasiracemates: benzoyl leucine and phenylalanine assemblies

Abstract

Quasiracemic materials constructed with two points of structural difference were used to understand the role molecular shape plays in molecular assembly. Hot stage, crystallographic and occupied cavity space assessments provide insight into how imposed CH3/Cl and H/CF3 structural variations placed on benzoyl leucine and phenylalanine scaffolds result in a remarkably high occurrence of cocrystal formation.

Graphical abstract: Dual space divergence in small molecule quasiracemates: benzoyl leucine and phenylalanine assemblies

Supplementary files

Article information

Article type
Communication
Submitted
21 Dec 2023
Accepted
11 Feb 2024
First published
12 Feb 2024

Chem. Commun., 2024,60, 2800-2803

Dual space divergence in small molecule quasiracemates: benzoyl leucine and phenylalanine assemblies

K. N. Koch, A. J. Teo and K. A. Wheeler, Chem. Commun., 2024, 60, 2800 DOI: 10.1039/D3CC06212K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements