Issue 11, 2024

Trifluoroethylamine-substituted solvatochromic fluorophores exhibit polarity-insensitive high brightness

Abstract

In this study, we have uncovered that trifluoroethylamine-substituted solvatochromic fluorophores maintain consistently high and stable fluorescence intensity in diverse polar environments, including highly polar and protic solvents. The 1,8-naphthalimide derivatives serve as a buffering fluorogenic indicator for lipid droplet morphology during the fusion process and ratiometric probe for microenvironment polarity based on Halo-tag technology.

Graphical abstract: Trifluoroethylamine-substituted solvatochromic fluorophores exhibit polarity-insensitive high brightness

Supplementary files

Article information

Article type
Communication
Submitted
30 Nov 2023
Accepted
06 Jan 2024
First published
08 Jan 2024

Chem. Commun., 2024,60, 1424-1427

Trifluoroethylamine-substituted solvatochromic fluorophores exhibit polarity-insensitive high brightness

N. Xu, Q. Qiao, J. Chen, Y. Tao, P. Bao, Y. Zhang, J. Li and Z. Xu, Chem. Commun., 2024, 60, 1424 DOI: 10.1039/D3CC05853K

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