Isocyanides are valuable compounds for organic synthesis. However, the poor stability and distressing odour have often limited their widespread applications in common laboratory practice and industrial settings. Herein, a continuous flow approach to enable the synthesis, purification and in-line reaction of isocyanides is presented.
B. Cerra, C. Blondeau, R. Cannalire, M. Giustiniano, S. Tali Shandiz and A. Gioiello, React. Chem. Eng., 2023, 8, 656 DOI: 10.1039/D2RE00454B
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