Synthesis of tetrazoles catalyzed by a new and recoverable nanocatalyst of cobalt on modified boehmite NPs with 1,3-bis(pyridin-3-ylmethyl)thiourea

Abstract

In the first part of this work, boehmite nanoparticles (BNPs) were synthesized from aqueous solutions of NaOH and Al(NO₃)₃·9H₂O. Then, the BNPs surface was modified using 3-choloropropyltrimtoxysilane (CPTMS) and then 1,3-bis(pyridin-3-ylmethyl)thiourea ((PYT)₂) was anchored on the surface of the modified BNPs (CPTMS@BNPs). In the final step, a complex of cobalt was stabilized on its surface (Co-(PYT)₂@BNPs). The final obtained nanoparticles were characterized by FT-IR spectra, TGA analysis, SEM imaging, WDX analysis, EDS analysis, and XRD patterns. In the second part, Co-(PYT)₂@BNPs were used as a highly efficient, retrievable, stable, and organic–inorganic hybrid nanocatalyst for the formation of organic heterocyclic compounds such as tetrazole derivatives. Co-(PYT)₂@BNPs as a novel nanocatalyst are stable and have a heterogeneous nature; therefore, they can be recovered and reused again for several consecutive runs without any re-activation.