Synthesis of diverse unsymmetric 1,4-adducts via a three-component coupling reaction of malonate derivatives, [60]fullerene and electrophiles/nucleophiles

Abstract

A three-component coupling reaction of malonate derivatives, [60]fullerene, and electrophiles/nucleophiles has been developed as a facile and efficient method to access various 1,4-unsymmetric malonate functionalized [60]fullerenes. This methodology features low cost, simple operation, transition metal-free nature and a wide range of substrates.