Issue 29, 2023

Synthesis of 3-aminoquinolines from α-imino rhodium carbenes and 2-aminobenzaldehydes

Abstract

A facile and efficient synthetic method for 3-aminoquinolines has been reported. The straightforward process starts from easily available triazoles and 2-aminobenzaldehydes. Low catalyst loading and good functional group compatibility are the other two merits of this transformation. Easy decoration of the 3-aminoquinoline motifs enabled the convenient synthesis of bioactive molecules, demonstrating the potential of this protocol in organic synthesis.

Graphical abstract: Synthesis of 3-aminoquinolines from α-imino rhodium carbenes and 2-aminobenzaldehydes

Supplementary files

Article information

Article type
Communication
Submitted
28 May 2023
Accepted
27 Jun 2023
First published
28 Jun 2023

Org. Biomol. Chem., 2023,21, 5935-5938

Synthesis of 3-aminoquinolines from α-imino rhodium carbenes and 2-aminobenzaldehydes

J. Li, J. Feng, T. Chen, Z. Xu and C. Li, Org. Biomol. Chem., 2023, 21, 5935 DOI: 10.1039/D3OB00843F

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