Issue 7, 2023
From the journal:

Organic & Biomolecular Chemistry

Sulfur(vi) fluorides as tools in biomolecular and medicinal chemistry

Sabrina N. Carneiro,†a   Samuel R. Khasnavis, ORCID logo †a   Jisun Lee, ORCID logo b   Todd W. Butler,b   Jaimeen D. Majmudar, ORCID logo c   Christopher W. am Ende*b  and  Nicholas D. Ball ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Pomona College, Claremont, California 91711, USA
E-mail: Nicholas.ball@pomona.edu

b Pfizer Worldwide Research, Development, Groton, Connecticut 06340, USA
E-mail: Christopher.amende@pfizer.com

c Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, USA

Abstract

Recent advances in the synthesis of sulfur(VI)-fluorides has enabled incredible growth in their application in biomolecular chemistry. This review aims to serve as a primer highlighting synthetic strategies toward a diversity of S(VI) fluorides and their application in chemical biology, bioconjugation, and medicinal chemistry.

Graphical abstract: Sulfur(vi) fluorides as tools in biomolecular and medicinal chemistry

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Article information

DOI
https://doi.org/10.1039/D2OB01891H
Article type
Review Article
Submitted
16 Oct 2022
Accepted
05 Jan 2023
First published
20 Jan 2023
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2023,21, 1356-1372

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Sulfur(VI) fluorides as tools in biomolecular and medicinal chemistry

S. N. Carneiro, S. R. Khasnavis, J. Lee, T. W. Butler, J. D. Majmudar, C. W. am Ende and N. D. Ball, Org. Biomol. Chem., 2023, 21, 1356 DOI: 10.1039/D2OB01891H

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