Lite Version|Standard version

To gain access to this content please
Log in with your free Royal Society of Chemistry publishing personal account.
Log in via your home Institution.
Log in with your member or subscriber username and password.
Download

Fluorescein, eosin Y, and rose bengal are dyes used in clinical medicine and considered (photo-)chemically stable. Upon extensive irradiation with visible light in aqueous solutions, we found that these compounds release carbon monoxide (CO) – a bioactive gasotransmitter – in 40–100% yields along with the production of low-mass secondary photoproducts, such as phthalic and formic acids, in a multistep degradation process. Such photochemistry should be considered in applications of these dyes, and they could also be utilized as visible-light activatable CO-releasing molecules (photoCORMs) with biological implications.

Graphical abstract: Common xanthene fluorescent dyes are visible-light activatable CO-releasing molecules

Page: ^ Top