PhI(OAc)2-mediated C–N bond cleavage of acylhydrazines with amines for the synthesis of amides†
Abstract
Amides are an important class of compounds in pharmaceutical and agrochemical chemistry. Herein, we report a novel procedure for the synthesis of amides via PhI(OAc)2-mediated C–N bond cleavage of acylhydrazines with amines under metal free conditions. The protocol shows broad substrate scope, high yields, and simple and mild operation.