A designed DNA/amino acid amphiphile-based supramolecular oxidase-mimetic catalyst for colorimetric DNA detection

Minquan Jiang; Shichao Xu; Yuanxi Liu; Zhen-Gang Wang

doi:10.1039/D3CC04047J

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A designed DNA/amino acid amphiphile-based supramolecular oxidase-mimetic catalyst for colorimetric DNA detection†

Minquan Jiang,^a Shichao Xu,^a Yuanxi Liu^a and Zhen-Gang Wang

*^a

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* Corresponding authors

^a State Key Laboratory of Organic–Inorganic Composites, Key Lab of Biomedical Materials of Natural Macromolecules (Ministry of Education), Beijing Laboratory of Biomedical Materials, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China
E-mail: wangzg@mail.buct.edu.cn

Abstract

DNA is self-assembled with Fmoc-amino acids and Cu²⁺ to construct a supramolecular catechol oxidase-mimetic catalyst, which exhibits remarkable activity in catalyzing colorimetric reactions. This catalytic system is used for the detection of DNA hybridization with a high selectivity and a low detection limit.

This article is part of the themed collection: Supramolecular & Macrocyclic chemistry

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Article information

DOI: https://doi.org/10.1039/D3CC04047J
Article type: Communication
Submitted: 21 Aug 2023
Accepted: 14 Nov 2023
First published: 14 Nov 2023

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Chem. Commun., 2023,59, 14540-14543

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A designed DNA/amino acid amphiphile-based supramolecular oxidase-mimetic catalyst for colorimetric DNA detection

M. Jiang, S. Xu, Y. Liu and Z. Wang, Chem. Commun., 2023, 59, 14540 DOI: 10.1039/D3CC04047J

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Chemical Communications

A designed DNA/amino acid amphiphile-based supramolecular oxidase-mimetic catalyst for colorimetric DNA detection†

Abstract

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A designed DNA/amino acid amphiphile-based supramolecular oxidase-mimetic catalyst for colorimetric DNA detection

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