Tunable vicinal, geminal diphosphorylation and C–N bond phosphorylation of enaminones toward divergent phosphorylated ketone derivatives

Abstract

This paper reports the trifunctionalization reactions of tertiary enaminones in the fashion of selective gem- and vicinal diphosphorylation, leading to the tunable synthesis of α,α- and α,β-diphosphoryl ketones. In addition, the C–N bond phosphorylation with improved substrate tolerance has been achieved.