Issue 37, 2023
From the journal:

Chemical Communications

A novel near-infrared fluorescent probe for the imaging of viscosity in cells and tumor-bearing mice†

Qin-Ting Liao,a   Jing-Jing Chao,a   Wen-Xin Wang,a   Ting Liu,a   Guo-Jiang Mao,b   Fen Xua  and  Chun-Yan Li ORCID logo *a  

* Corresponding authors

a Key Laboratory for Green Organic Synthesis and Application of Hunan Province, Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan, P. R. China
E-mail: lichunyan79@sina.com

b Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, P. R. China

Abstract

A near-infrared fluorescent probe (IC-V) for detecting viscosity is constructed. The probe has a large Stokes shift (170 nm) and an about 180-fold increase in fluorescence intensity at 700 nm. In addition, IC-V can not only distinguish cancer cells from normal cells, but also monitor viscosity in normal mice and tumor-bearing mice.

Graphical abstract: A novel near-infrared fluorescent probe for the imaging of viscosity in cells and tumor-bearing mice

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Article information

DOI
https://doi.org/10.1039/D3CC01101A
Article type
Communication
Submitted
06 Mar 2023
Accepted
12 Apr 2023
First published
12 Apr 2023

Chem. Commun., 2023,59, 5607-5610

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A novel near-infrared fluorescent probe for the imaging of viscosity in cells and tumor-bearing mice

Q. Liao, J. Chao, W. Wang, T. Liu, G. Mao, F. Xu and C. Li, Chem. Commun., 2023, 59, 5607 DOI: 10.1039/D3CC01101A

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