Homogeneous voltammetric sensing strategy for lead ions based on aptamer gated methylthionine chloride@UiO-66-NH2 framework as smart target-stimulated responsive nanomaterial

Abstract

Herein an innovative electrochemical method is proposed for the determination of lead ions (Pb²⁺) based on a homogeneous voltammetric (HVC) sensing strategy using an aptamer gated methylthionine chloride@UiO-66-NH₂ framework as a smart target-stimulated responsive material. The proposed HVC sensor exhibits excellent sensing performance: ultralow detection limit (0.166 pM) and wide linearity (5.0 pM–500.0 nM), simultaneously, it avoids electrodeposition processes and it is simple to modify the electrode compared to previous electrochemical methods for Pb²⁺ detection. Thus our method shows great potential in the highly efficient detection of Pb²⁺ and other heavy metal ions by simply altering the related specific aptamer.