Issue 39, 2023

Designing protein nano-construct in ionic liquid: a boost in efficacy of cytochrome C under stresses

Abstract

Herein, we present a simple approach to fabricate protein nanoconstructs by complexing cytochrome C (Cyt C) with silk nanofibrils (SNF) and choline dihydrogen phosphate ionic liquid (IL). The peroxidase activity of the IL modified Cyt C nanoconstruct (Cyt C + SNF + IL) increased significantly (2.5 to 10-fold) over unmodified Cyt C and showed enhanced catalytic activity and stability under harsh conditions, proving its potential as a suitable protein packaging strategy.

Graphical abstract: Designing protein nano-construct in ionic liquid: a boost in efficacy of cytochrome C under stresses

Supplementary files

Article information

Article type
Communication
Submitted
12 Feb 2023
Accepted
18 Apr 2023
First published
21 Apr 2023
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2023,59, 5894-5897

Designing protein nano-construct in ionic liquid: a boost in efficacy of cytochrome C under stresses

S. K. Thayallath, S. M. Shet, M. Bisht, P. Bharadwaj, M. M. Pereira, G. Franklin, S. K. Nataraj and D. Mondal, Chem. Commun., 2023, 59, 5894 DOI: 10.1039/D3CC00644A

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements