Issue 39, 2023
From the journal:

Chemical Communications

Designing protein nano-construct in ionic liquid: a boost in efficacy of cytochrome C under stresses†

Sarath Kumar Thayallath,‡a   Sachin M. Shet,‡a   Meena Bisht,b   Pranav Bharadwaj,a   Matheus M. Pereira, ORCID logo c   Gregory Franklin, ORCID logo b   S. K. Nataraj ORCID logo a  and  Dibyendu Mondal ORCID logo *ab  

* Corresponding authors

a Centre for Nano and Material Sciences, Jain (Deemed-to-be University), Jain Global Campus, Kanakapura, Bangalore, Karnataka, India
E-mail: dmtapu@gmail.com, dmon@igr.poznan.pl

b Institute of Plant Genetics (IPG), Polish Academy of Sciences, Strzeszynska 34, 60-479 Poznan, Poland

c University of Coimbra, CIEPQPF, Department of Chemical Engineering, Rua Silvio Lima, Polo II – Pinhal de Marrocos, 3030-790 Coimbra, Portugal

Abstract

Herein, we present a simple approach to fabricate protein nanoconstructs by complexing cytochrome C (Cyt C) with silk nanofibrils (SNF) and choline dihydrogen phosphate ionic liquid (IL). The peroxidase activity of the IL modified Cyt C nanoconstruct (Cyt C + SNF + IL) increased significantly (2.5 to 10-fold) over unmodified Cyt C and showed enhanced catalytic activity and stability under harsh conditions, proving its potential as a suitable protein packaging strategy.

Graphical abstract: Designing protein nano-construct in ionic liquid: a boost in efficacy of cytochrome C under stresses

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Article information

DOI
https://doi.org/10.1039/D3CC00644A
Article type
Communication
Submitted
12 Feb 2023
Accepted
18 Apr 2023
First published
21 Apr 2023
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2023,59, 5894-5897

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Designing protein nano-construct in ionic liquid: a boost in efficacy of cytochrome C under stresses

S. K. Thayallath, S. M. Shet, M. Bisht, P. Bharadwaj, M. M. Pereira, G. Franklin, S. K. Nataraj and D. Mondal, Chem. Commun., 2023, 59, 5894 DOI: 10.1039/D3CC00644A

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