Regioselective synthesis of phenanthridine-fused quinazolinones using a 9-mesityl-10-methylacridinium perchlorate photocatalyst

Abstract

Herein, we demonstrate a regioselective intramolecular C–N cross-coupling for the synthesis of 14H-quinazolino[3,2-f]phenanthridin-14-one by using 9-mesityl-10-methylacridinium perchlorate as the visible-light (450–470 nm) photocatalyst. The experiments with BHT, TEMPO, and Stern–Volmer quenching studies helped to rationalize a radical pathway via a SET mechanism.