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Abstract | Cited by

An “AND” logic gate-based NIR fluorescent probe Si-NH2-Glu was developed based on novel meso-amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and pH dual-responsive sites. The features of Si-NH2-Glu enable it to be applied in orthotopic tumor imaging and fluorescence-guided surgery.

Graphical abstract: γ-Glutamyltranspeptidase and pH based “AND” logic gate fluorescent probe for orthotopic breast tumor imaging

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