Yusuke Matsui, Toshiyuki Kowada, Yi Ding, Priya Ranjan Sahoo, Kazuya Kikuchi and Shin Mizukami
Chem. Commun., 2023,59, 7048-7051
DOI:
10.1039/D2CC05930D,
Communication
A novel fluorescent Mg2+ probe was developed based on a small molecule–protein hybrid. This probe enables subcellular targeting, long-term imaging, and high selectivity for Mg2+ over Ca2+. Using ratiometric fluorescence microscopy with a co-localized standard fluorophore, the variations in intranuclear Mg2+ concentrations during mitosis could be visualized.