Issue 6, 2023

Highly selective γ-alkoxylation, γ-amination and γ-alkylation of unbiased enals by means of photoredox catalysis

Abstract

We report herein a general and highly selective γ-functionalization protocol under visible light irradiation. This mild radical approach enables the expansion of the scope of application to unbiased enals and the introduction of a wide variety of alkoxy, amino and alkyl functionalities in the γ position with complete regioselectivity.

Graphical abstract: Highly selective γ-alkoxylation, γ-amination and γ-alkylation of unbiased enals by means of photoredox catalysis

Supplementary files

Article information

Article type
Communication
Submitted
22 Oct 2022
Accepted
12 Dec 2022
First published
13 Dec 2022

Chem. Commun., 2023,59, 760-763

Highly selective γ-alkoxylation, γ-amination and γ-alkylation of unbiased enals by means of photoredox catalysis

C. Banoun, F. Bourdreux and G. Dagousset, Chem. Commun., 2023, 59, 760 DOI: 10.1039/D2CC05749B

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