Magnetic covalent organic frameworks for rapid solid-phase extraction of phthalate esters and bisphenol A in beverage samples

Abstract

Phthalate esters (PAEs) and bisphenol A (BPA) are endocrine-disrupting chemicals (EDCs), which are widely used in the production of food plastic packaging and easily migrate to food. Continuous exposure to EDCs may cause harm to human health. Herein, magnetic covalent organic framework TFP-NDA/Fe₃O₄ was synthesized by magnetizing covalent organic framework TFP-NDA through a facile coprecipitation method, and used as an adsorbent for rapid solid-phase extraction of PAEs (diethyl phthalate (DEP), diisobutyl phthalate (DIBP) and dibutyl phthalate (DBP)) and BPA. The extraction equilibrium can be reached within 12 min. By combination with a gas chromatography-flame ionization detector, the limits of detection were 0.7–2.3 μg L⁻¹ and the linear ranges were 10–500 μg L⁻¹ for diethyl phthalate (DEP) and 10–1000 μg L⁻¹ for diisobutyl phthalate (DIBP), dibutyl phthalate (DBP) and BPA with R² > 0.9916. In beverage samples (plastic bottled drinking water, juice and carbonated drink), the developed method was successfully applied to extract and quantify PAEs and BPA with recoveries ranging from 81.7% to 114.2%.