Issue 37, 2022

Magnetomechanical force: an emerging paradigm for therapeutic applications

Abstract

Mechanical forces, which play a profound role in cell fate regulation, have prompted the rapid development and popularization of mechanobiology. More recently, magnetic fields in combination with intelligent materials featuring magnetic responsiveness have been identified as a spatially and time-controlled transducing paradigm to generate magnetomechanical forces and induce a therapeutic effect. Herein, recent magnetic materials and magnetic regulation systems are summarized, which offer opportunities for magnetomechanical force manipulation in a precise manner. Additionally, promising applications based on magnetomechanical force including drug controlled release, cancer therapy, and regenerative medicine are highlighted, with respect to both in vitro and in vivo. Furthermore, perspectives on the further development of magnetomechanical force are commented on, mainly emphasizing scientific restrictions and exploitation directions.

Graphical abstract: Magnetomechanical force: an emerging paradigm for therapeutic applications

Article information

Article type
Review Article
Submitted
28 Feb 2022
Accepted
27 Apr 2022
First published
28 Apr 2022

J. Mater. Chem. B, 2022,10, 7136-7147

Magnetomechanical force: an emerging paradigm for therapeutic applications

J. Yao, C. Yao, A. Zhang, X. Xu, A. Wu and F. Yang, J. Mater. Chem. B, 2022, 10, 7136 DOI: 10.1039/D2TB00428C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements