Issue 14, 2022

Mechanically interlocked molecular handcuffs


The field of mechanically interlocked molecules that employ a handcuff component are reviewed. The variety of rotaxane and catenane structures that use the handcuff motif to interlock different components are discussed and a new nomenclature, distilling diverse terminologies to a single approach, is proposed. By unifying the interpretation of this class of molecules we identify new opportunities for employing this structural unit for new architectures.

Graphical abstract: Mechanically interlocked molecular handcuffs

Article information

Article type
28 Jan 2022
27 Feb 2022
First published
16 Mar 2022
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2022,13, 3915-3941

Mechanically interlocked molecular handcuffs

N. Pearce, M. Tarnowska, N. J. Andersen, A. Wahrhaftig-Lewis, B. S. Pilgrim and N. R. Champness, Chem. Sci., 2022, 13, 3915 DOI: 10.1039/D2SC00568A

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