Issue 29, 2022
From the journal:

RSC Advances

Ultrasonic-assisted-synthesis of isoindolin-1-one derivatives†

Muhammad Idham Darussalam Mardjan, ORCID logo *a   Muhamad Fadhly Hariadi, ORCID logo a   Indah Mutiara Putri, ORCID logo a   Nilna Amalia Musyarrofah,a   Muflihah Salimah,a   Priatmoko,a   Bambang Purwonoa  and  Laurent Commeiras ORCID logo b  

* Corresponding authors

a Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Bulaksumur POS BLS 21, Yogyakarta 55281, Indonesia
E-mail: idham.darussalam@ugm.ac.id

b Aix Marseille Univ., CNRS, Centrale Marseille, iSm2, Marseille 13013, France

Abstract

A small library of 3-hydroxyisoindolin-1-ones has been prepared from 3-alkylidenephtalides under ultrasonic irradiation. This practical synthesis is featured by group tolerance, high efficiency and yields. The reaction can also be performed in multigram scale and be further extended to access other motifs of isoindolin-1-ones in a one-pot fashion.

Graphical abstract: Ultrasonic-assisted-synthesis of isoindolin-1-one derivatives

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Article information

DOI
https://doi.org/10.1039/D2RA02720H
Article type
Paper
Submitted
29 Apr 2022
Accepted
15 Jun 2022
First published
29 Jun 2022
This article is Open Access
Creative Commons BY license

RSC Adv., 2022,12, 19016-19021

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Ultrasonic-assisted-synthesis of isoindolin-1-one derivatives

M. I. D. Mardjan, M. F. Hariadi, I. M. Putri, N. A. Musyarrofah, M. Salimah, Priatmoko, B. Purwono and L. Commeiras, RSC Adv., 2022, 12, 19016 DOI: 10.1039/D2RA02720H

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