Thioamide directed iridium(i)-catalyzed C–H arylation of ferrocenes with aryl boronic acids†
Abstract
The first Ir(I)-catalyzed thioamide-assisted C–H arylation of ferrocenes with aryl boronic acids under base-free mild reaction conditions in the presence of Ag2CO3 as an oxidant with eco-friendly 2-MeTHF as a solvent was developed. This reaction has a wide range of substrates (37 examples) and functional group tolerance (18–94% yields), and provides promising access to aryl thioamide-ferrocene compounds with good yields and regioselectivity.