Lei He, Chenfeng Liang, Yani Ouyang, Lin Li, Yirui Guo, Pengfei Zhang and Wanmei Li
Org. Biomol. Chem., 2022,20, 790-795
DOI:
10.1039/D1OB02249K,
Communication
Herein, a protocol that combines heterogeneous catalysis and solar photocatalysis for the regioselective α-substitution of asymmetric ketones with quinoxalinones has been reported. The result indicates that the reaction is more likely to occur on the α-carbon. This strategy provides a green and efficient way for the α-functionalization of ketones. A singlet oxygen involved mechanism is suggested for the transformation.
