Issue 2, 2022

Recent advances in palladium-catalyzed C(sp3)/C(sp2)–H bond functionalizations: access to C-branched glycosides

Abstract

Over the recent decades, tremendous interest has developed in the transformation of complex substrates by C–H activation and functionalization. In particular, palladium-catalyzed directing and non-directing group-assisted C–H functionalization has emerged as a powerful avenue to access C-branched glycosides. Due to the extreme complexity, delicate functionalities, and high stability of C–H bonds, site-selective functionalization of carbohydrate under mild conditions is highly desirable. The purpose of this review is to cover most of the recent advances in palladium-catalyzed C(sp3) and C(sp2)–H bond functionalizations for the synthesis of C-branched glycosides along with future directions.

Graphical abstract: Recent advances in palladium-catalyzed C(sp3)/C(sp2)–H bond functionalizations: access to C-branched glycosides

Article information

Article type
Review Article
Submitted
01 Nov 2021
Accepted
23 Nov 2021
First published
23 Nov 2021

Org. Biomol. Chem., 2022,20, 264-281

Recent advances in palladium-catalyzed C(sp3)/C(sp2)–H bond functionalizations: access to C-branched glycosides

Z. Azeem and P. K. Mandal, Org. Biomol. Chem., 2022, 20, 264 DOI: 10.1039/D1OB02142G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements