Steve Huvelle, Thomas Le Saux, Ludovic Jullien and Frédéric Schmidt
Org. Biomol. Chem., 2022,20, 240-246
DOI:
10.1039/D1OB02124A,
Paper
A self-immolative spacer based on dissymmetrical N,N′-bis-carbamate aniline is introduced to liberate a substrate from a precursor after dual activation. The proof of principle of its exclusive selectivity for substrate liberation has been conducted on a profluorophore.