Issue 30, 2022
From the journal:

New Journal of Chemistry

A novel fluorescent probe for the detection of Golgi nitroreductase under hypoxic conditions†

Qian Zhang, ORCID logo a   Yonghe Tang, ORCID logo a   Sirui Song,a   Juanjuan Penga  and  Weiying Lin ORCID logo *a  

* Corresponding authors

a Guangxi Key Laboratory of Electrochemical Energy Materials, Institute of Optical Materials and Chemical Biology, School of Chemistry and Chemical Engineering, MOE Key Laboratory of New Processing Technology for Nonferrous Metals and Materials, Guangxi Key Laboratory of Processing for Non-ferrous Metals and Featured Materials, Guangxi University, Nanning 530004, China
E-mail: weiyinglin2013@163.com

Abstract

The first Golgi-targeted fluorescent probe (named Gol-NTR) for detecting nitroreductase (NTR) was developed. Gol-NTR had good selectivity for NTR and low cytotoxicity. Furthermore, it is worth noting that Gol-NTR was successfully applied to the detection of NTR in the Golgi apparatus, for the first time.

Graphical abstract: A novel fluorescent probe for the detection of Golgi nitroreductase under hypoxic conditions

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Article information

DOI
https://doi.org/10.1039/D2NJ02326A
Article type
Communication
Submitted
12 May 2022
Accepted
08 Jul 2022
First published
08 Jul 2022

New J. Chem., 2022,46, 14333-14337

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A novel fluorescent probe for the detection of Golgi nitroreductase under hypoxic conditions

Q. Zhang, Y. Tang, S. Song, J. Peng and W. Lin, New J. Chem., 2022, 46, 14333 DOI: 10.1039/D2NJ02326A

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