K2S2O8-induced site-selective phenoxazination/phenothiazination of electron-rich anilines

Abstract

By just using cheap K₂S₂O₈ as the oxidant at room temperature in the air, the phenoxazination/phenothiazination of electron-rich anilines to construct or modify triarylamine derivatives has been established. This method demonstrates complete para-selective amination under catalyst-free conditions and its simplicity and efficiency lead to good performance in flow-chemistry synthesis.