Issue 85, 2022

A long-wavelength xanthene dye for photoacoustic imaging

Abstract

Photoacoustic (PA) imaging is a powerful biomedical imaging modality. We designed KeTMR and KeJuR, two xanthene-based dyes that were readily obtained through a 2-step synthetic route. KeJuR has low molecular weight, good aqueous solubility, and superior chemical stability compared to KeTMR. KeJuR shows a robust PA signal under 860 nm excitation and can be paired with traditional PA dyes for multiplex imaging in blood samples under a tissue-mimicking environment.

Graphical abstract: A long-wavelength xanthene dye for photoacoustic imaging

Supplementary files

Article information

Article type
Communication
Submitted
14 Jul 2022
Accepted
30 Aug 2022
First published
05 Oct 2022

Chem. Commun., 2022,58, 11941-11944

A long-wavelength xanthene dye for photoacoustic imaging

X. Zhou, Y. Fang, V. Wimalasiri, C. I. Stains and E. W. Miller, Chem. Commun., 2022, 58, 11941 DOI: 10.1039/D2CC03947H

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