Ru(II)-catalyzed P(III)-assisted C8-alkylation of naphthphosphines

Wen-Tao Ma; Mao-Gui Huang; Yueliuting Fu; Zhong-Hui Wang; Jun-Yang Tao; Jia-Wei Li; Yue-Jin Liu; Ming-Hua Zeng

doi:10.1039/D2CC02161G

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Ru^(II)-catalyzed P^(III)-assisted C8-alkylation of naphthphosphines†

Wen-Tao Ma,^a Mao-Gui Huang,^a Yueliuting Fu,^a Zhong-Hui Wang,^a Jun-Yang Tao,^a Jia-Wei Li,^a Yue-Jin Liu

*^a and Ming-Hua Zeng

*^ab

Author affiliations

* Corresponding authors

^a Collaborative Innovation Center for Advanced Organic Chemical Materials Co-constructed by the Province and Ministry, Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, and College of Chemistry and Chemical Engineering, Hubei University, Wuhan, China
E-mail: liuyuejin@hubu.edu.cn

^b State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, China
E-mail: zmh@mailbox.gxnu.edu.cn

Abstract

We report a phosphine-directed ruthenium-catalyzed C8-selective alkylation of naphthalenes with alkenes. This protocol provides straightforward access to a large library of electron-rich C8-alkyl substituent 1-naphthphosphines, which outperformed common commercial phosphines and their precursors in the Pd-catalyzed Suzuki–Miyaura coupling of aryl bromides with alkylboronic acid.

Download options Please wait...

Supplementary files

Article information

DOI: https://doi.org/10.1039/D2CC02161G
Article type: Communication
Submitted: 15 Apr 2022
Accepted: 26 May 2022
First published: 26 May 2022

Download Citation

Chem. Commun., 2022,58, 7152-7155

Permissions

Request permissions

Ru^(II)-catalyzed P^(III)-assisted C8-alkylation of naphthphosphines

W. Ma, M. Huang, Y. Fu, Z. Wang, J. Tao, J. Li, Y. Liu and M. Zeng, Chem. Commun., 2022, 58, 7152 DOI: 10.1039/D2CC02161G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications