Issue 59, 2022
From the journal:

Chemical Communications

Lanmodulin remains unfolded and fails to interact with lanthanide ions in Escherichia coli cells†

Qiong Wu,ab   Xiaoli Liu,a   Zhaofei Chai,a   Kai Cheng,a   Guohua Xu,a   Ling Jiang,a   Maili Liu ORCID logo a  and  Conggang Li ORCID logo *ab  

* Corresponding authors

a Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan National Laboratory for Optoelectronics, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China
E-mail: conggangli@wipm.ac.cn
Fax: +86 27 87199291

b Graduate University of Chinese Academy of Sciences, Beijing, China

Abstract

We report the conformation of a newly discovered specific lanthanide ion (Ln3+) binding protein, lanmodulin (LanM), and its interaction with Ln3+ in Escherichia coli cells using the in-cell NMR technique. We found that LanM remains unfolded and fails to bind Ln3+ in Escherichia coli cells due to the abundance of phosphate groups.

Graphical abstract: Lanmodulin remains unfolded and fails to interact with lanthanide ions in Escherichia coli cells

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D2CC02038F
Article type
Communication
Submitted
10 Apr 2022
Accepted
20 Jun 2022
First published
21 Jun 2022

Chem. Commun., 2022,58, 8230-8233

Permissions

Request permissions

Lanmodulin remains unfolded and fails to interact with lanthanide ions in Escherichia coli cells

Q. Wu, X. Liu, Z. Chai, K. Cheng, G. Xu, L. Jiang, M. Liu and C. Li, Chem. Commun., 2022, 58, 8230 DOI: 10.1039/D2CC02038F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements