Asymmetric cyclopropanation of electron-rich alkenes by the racemic diene rhodium catalyst: the chiral poisoning approach†
Evgeniya A.
Trifonova, 
a
Nikita M.
Ankudinov,
a
Denis A.
Chusov,
a
Yulia V.
Nelyubina
a
and
Dmitry S.
Perekalin
*a
a
Nikita M.
Ankudinov,
a
Denis A.
Chusov,
a
Yulia V.
Nelyubina
a
and
Dmitry S.
Perekalin
*a
Abstract
Asymmetric cyclopropanation of alkenes by aryldiazoacetates was achieved using the readily-available racemic (diene)rhodium complex in combination with the chiral oxazoline-phenol ligand, which acts as the chiral poison and selectively inhibits one of the enantiomers of the catalyst. This approach eliminates a common problematic step of the synthesis of chiral catalysts.
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