Issue 36, 2022

SHARPER-enhanced benchtop NMR: improving SNR by removing couplings and approaching natural linewidths

Abstract

We present a signal enhancement strategy for benchtop NMR that produces SNR increases on the order of 10 to 30 fold by collapsing the target resonance into an extremely narrow singlet. Importantly, the resultant signal is amenable to quantitative interpretation and therefore can be applied to analytical applications such as reaction monitoring.

Graphical abstract: SHARPER-enhanced benchtop NMR: improving SNR by removing couplings and approaching natural linewidths

Supplementary files

Article information

Article type
Communication
Submitted
06 Mar 2022
Accepted
04 Apr 2022
First published
05 Apr 2022
This article is Open Access
Creative Commons BY license

Chem. Commun., 2022,58, 5534-5537

SHARPER-enhanced benchtop NMR: improving SNR by removing couplings and approaching natural linewidths

C. L. Dickson, G. Peat, M. Rossetto, M. E. Halse and D. Uhrín, Chem. Commun., 2022, 58, 5534 DOI: 10.1039/D2CC01325H

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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