Bicyclic (alkyl)(amino)carbene (BICAAC) is introduced as a metal-free catalyst for the reduction of various nitriles to the corresponding amine hydrochloride salts in the presence of pinacolborane. Mechanistic investigations combining experiments and DFT calculations suggest a B–H addition to the carbene center, which acts as a carrier of the hydride source.
N. Gautam, R. Logdi, Sreejyothi P., N. M. Rajendran, A. K. Tiwari and S. K. Mandal, Chem. Commun., 2022, 58, 3047 DOI: 10.1039/D1CC06962D
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