Issue 16, 2022

Exploring graphene oxide intrinsic electroactivity to elucidate the non-covalent interactions with DNA oligonucleotides

Abstract

We show here how the electrochemical reduction signal of graphene oxide nanocolloids is inhibited upon the formation of non-covalent interactions with single stranded DNA oligonucleotides. The drop in the reduction current intensity is strongly influenced by the nucleobase sequence, and can therefore be directly correlated to the specific DNA homo-oligonucleotide.

Graphical abstract: Exploring graphene oxide intrinsic electroactivity to elucidate the non-covalent interactions with DNA oligonucleotides

Supplementary files

Article information

Article type
Communication
Submitted
26 Nov 2021
Accepted
25 Jan 2022
First published
02 Feb 2022

Chem. Commun., 2022,58, 2662-2665

Exploring graphene oxide intrinsic electroactivity to elucidate the non-covalent interactions with DNA oligonucleotides

Y. Liang, W. L. Ang, R. R. X. Lim and A. Bonanni, Chem. Commun., 2022, 58, 2662 DOI: 10.1039/D1CC06657A

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