Issue 8, 2021

Recent development in transition metal-catalysed C–H olefination

Abstract

Transition metal-catalysed functionalizations of inert C–H bonds to construct C–C bonds represent an ideal route in the synthesis of valuable organic molecules. Fine tuning of directing groups, catalysts and ligands has played a crucial role in selective C–H bond (sp2 or sp3) activation. Recent developments in these areas have assured a high level of regioselectivity in C–H olefination reactions. In this review, we have summarized the recent progress in the oxidative olefination of sp2 and sp3 C–H bonds with special emphasis on distal, atroposelective, non-directed sp2 and directed sp3 C–H olefination. The scope, limitation, and mechanism of various transition metal-catalysed olefination reactions have been described briefly.

Graphical abstract: Recent development in transition metal-catalysed C–H olefination

Article information

Article type
Review Article
Submitted
08 Oct 2020
Accepted
28 Dec 2020
First published
29 Jan 2021
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY-NC license

Chem. Sci., 2021,12, 2735-2759

Recent development in transition metal-catalysed C–H olefination

W. Ali, G. Prakash and D. Maiti, Chem. Sci., 2021, 12, 2735 DOI: 10.1039/D0SC05555G

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