Issue 35, 2021, Issue in Progress

Microwave-assisted green construction of imidazole-fused hybrid scaffolds using 2-aminobenzimidazoles as building blocks

Abstract

A class of trinuclear imidazole-fused hybrid scaffolds was constructed by the reaction of 2-(2-bromoaryl)- and 2-(2-bromovinyl)imidazoles with 2-aminobenzimidazoles as building blocks in the presence of a base under microwave irradiation. A nucleophilic aromatic substitution followed by cyclization is proposed as a reaction pathway of this green process.

Graphical abstract: Microwave-assisted green construction of imidazole-fused hybrid scaffolds using 2-aminobenzimidazoles as building blocks

Supplementary files

Article information

Article type
Paper
Submitted
07 Jun 2021
Accepted
08 Jun 2021
First published
17 Jun 2021
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2021,11, 21367-21374

Microwave-assisted green construction of imidazole-fused hybrid scaffolds using 2-aminobenzimidazoles as building blocks

J. P. Kwak, P. D. Quang Dao, N. S. Yoon and C. S. Cho, RSC Adv., 2021, 11, 21367 DOI: 10.1039/D1RA04396J

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