Issue 22, 2021

Recent approaches in the organocatalytic synthesis of pyrroles


Organocatalysis has emerged as one of the most important tools for the synthesis of diverse structural scaffolds, and has become one of the most important hot topics of current research. Construction of the pyrrole ring has gained much attention from the last few decades due to its remarkable biological activities, pharmaceutical application, intermediate in the synthesis of many natural products, and material science application. With access to these 5-membered aza heterocycles, organocatalytic approaches have provided a new alternative from the perspective of synthetic efficiency, as well as from the green chemistry point of view, and a vast array of synthetic procedures has been developed. Enlightened by the significance of this growing research area, we aim to describe the recent organocatalytic approaches developed for the construction of pyrroles, and organized them based on substrates employed.

Graphical abstract: Recent approaches in the organocatalytic synthesis of pyrroles

Article information

Article type
Review Article
03 Mar 2021
24 Mar 2021
First published
13 Apr 2021
This article is Open Access
Creative Commons BY license

RSC Adv., 2021,11, 13585-13601

Recent approaches in the organocatalytic synthesis of pyrroles

B. Borah, K. D. Dwivedi and L. R. Chowhan, RSC Adv., 2021, 11, 13585 DOI: 10.1039/D1RA01690C

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