Issue 7, 2021, Issue in Progress
From the journal:

RSC Advances

Synthesis of fully protected trinucleotide building blocks on a disulphide-linked soluble support†

Ruth Suchsland,a   Bettina Appel, ORCID logo a   Pasi Virta ORCID logo b  and  Sabine Müller ORCID logo *a  

* Corresponding authors

a University Greifswald, Institute for Biochemistry, 17487 Greifswald, Germany

b University of Turku, Department of Chemistry, 20014 Turku, Finland
E-mail: smueller@uni-greifswald.de

Abstract

In recent years, preparation of fully protected trinucleotide phosphoramidites as synthons for the codon-based synthesis of gene libraries as well as for the assembly of oligonucleotides from blockmers has gained much attention. We here describe the preparation of such trinucleotide synthons on a soluble support using a disulphide linker.

Graphical abstract: Synthesis of fully protected trinucleotide building blocks on a disulphide-linked soluble support

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D0RA10941J
Article type
Paper
Submitted
30 Dec 2020
Accepted
12 Jan 2021
First published
20 Jan 2021
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2021,11, 3892-3896

Permissions

Request permissions

Synthesis of fully protected trinucleotide building blocks on a disulphide-linked soluble support

R. Suchsland, B. Appel, P. Virta and S. Müller, RSC Adv., 2021, 11, 3892 DOI: 10.1039/D0RA10941J

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements