Graphdiyne nanosheets as a platform for accurate copper(II) ion detection via click chemistry and fluorescence resonance energy transfer

Chenchen Ge; Jiaofu Li; Dou Wang; Kongpeng Lv; Quan Liu; Yan Shen; Xiaoqing Zhuang; Wankun Luo; Zongze Wu; Yuhua Zhang; Lulin Shi; Liping Liu; Shiyun Bao; Han Zhang

doi:10.1039/D0RA08595B

Graphdiyne nanosheets as a platform for accurate copper(ii) ion detection via click chemistry and fluorescence resonance energy transfer†

Chenchen Ge,‡^ac Jiaofu Li,‡^b Dou Wang,‡^d Kongpeng Lv,^a Quan Liu,^a Yan Shen,^a Xiaoqing Zhuang,^a Wankun Luo,^a Zongze Wu,^a Yuhua Zhang,^a Lulin Shi,^a Liping Liu,*^a Shiyun Bao*^a and Han Zhang

*^b

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^a Department of Hepatobiliary and Pancreatic Surgery, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Shenzhen, China
E-mail: bao.shiyun@szhospital.com, liu.liping@szhospital.com

^b Institute of Microscale Optoelectronics, Collaborative Innovation Centre for Optoelectronic Science & Technology, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ), Shenzhen University, Shenzhen, PR China
E-mail: hzhang@szu.edu.cn

^c College of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen, China

^d Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, China

Abstract

A novel sensing platform for sensitive detection of copper(II) ions (Cu²⁺) in living cells and body fluids was developed by taking advantage of the excellent fluorescence quenching ability of graphdiyne (GDY) and the high specificity of click chemistry for the first time.

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Graphdiyne nanosheets as a platform for accurate copper(ii) ion detection via click chemistry and fluorescence resonance energy transfer†

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Graphdiyne nanosheets as a platform for accurate copper(II) ion detection via click chemistry and fluorescence resonance energy transfer

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